SCHEMBL25674244

SCHEMBL25674244

CCOC(=O)/C(=N\N)C(=O)c1c(F)cccc1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
RAB9A P51151 3/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
NLRP3 Q96P20 1/20 0.36
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
NPC1 O15118 2/20 0.34
CYP1A2 P05177 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30398353 1.00 SMN1; SMN2 (0.40) SMN1; SMN2RAB9ACES2CES1NLRP3
SCHEMBL25674029 0.85 POLB (0.43) SMN1; SMN2RAB9ACES2CES1ALDH1A1
SCHEMBL25209709 0.79 CES2 (0.44) CES2CES1LMNAHTTKMT2A
SCHEMBL3716153 0.79 CES2 (0.47) SMN1; SMN2RAB9ACES2CES1ALDH1A1
SCHEMBL3716151 0.79 CES2 (0.47) SMN1; SMN2RAB9ACES2CES1ALDH1A1
SCHEMBL14352262 0.76 CA12 (0.56) RAB9ACES2CES1NLRP3ALDH1A1
SCHEMBL19398668 0.74 MEN1 (0.42) SMN1; SMN2CES2CES1ALDH1A1KDM4E
SCHEMBL14605537 0.74 CES2 (0.57) SMN1; SMN2RAB9ACES2CES1NLRP3
SCHEMBL3710783 0.72 CYP11B1 (0.40) SMN1; SMN2NLRP3ALDH1A1KDM4ETSHR
SCHEMBL25204360 0.71 NLRP3 (0.49) SMN1; SMN2RAB9ACES2CES1NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265705-A Herbicidal derivatives 先正达农作物保护股份公司 2024-06-28 CN disclosed
WO-2023088921-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-05-25 WO disclosed