Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813568 | 0.76 | TSHR (0.42) | TSHRLMNATYRKIF11CYP1A2 | |
| SCHEMBL1956921 | 0.72 | CYP1A2 (0.42) | TSHRLMNACYP1A2ALDH1A1MEN1 | |
| SCHEMBL8076654 | 0.72 | MEN1 (0.37) | TSHRLMNACYP1A2ALDH1A1ACHE | |
| SCHEMBL8076656 | 0.72 | MEN1 (0.37) | TSHRLMNACYP1A2ALDH1A1ACHE | |
| SCHEMBL14163841 | 0.71 | TSHR (0.52) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL13136660 | 0.71 | TSHR (0.52) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL6705565 | 0.71 | TSHR (0.52) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL10000752 | 0.69 | CYP1A2 (0.47) | TSHRLMNATYRCYP1A2ALDH1A1 | |
| SCHEMBL424728 | 0.69 | TSHR (0.73) | TSHRLMNATYRKIF11CYP1A2 | |
| SCHEMBL15494 | 0.69 | TSHR (0.61) | TSHRLMNATYRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3404735-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2023-05-10 | — | — | EP | disclosed |