Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229782 | 0.98 | HIF1A (0.33) | RXFP1L3MBTL1HIF1AMEN1NPC1 | |
| SCHEMBL27971601 | 0.76 | KDM1A (0.32) | RXFP1 | |
| SCHEMBL2983952 | 0.75 | HIF1A (0.33) | RXFP1L3MBTL1HIF1AMEN1NPC1 | |
| SCHEMBL8052199 | 0.73 | ALDH1A1 (0.51) | RXFP1L3MBTL1HIF1AMEN1NPC1 | |
| SCHEMBL5031067 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL27875481 | 0.72 | OPRM1 (0.49) | RXFP1SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL3239387 | 0.70 | ALDH1A1 (0.46) | L3MBTL1HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL3241413 | 0.69 | OPRM1 (0.50) | SLC6A2SLC6A4SLC6A3HIF1AALDH1A1 | |
| SCHEMBL28298245 | 0.68 | OPRM1 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2565999 | 0.68 | PDE4A (0.46) | RXFP1PDE4AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382240-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085622-A9 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010085622-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |