⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726154 | 0.81 | — | — | |
| SCHEMBL2569586 | 0.79 | — | — | |
| SCHEMBL5439184 | 0.78 | — | — | |
| SCHEMBL1322409 | 0.77 | — | — | |
| SCHEMBL4830633 | 0.77 | — | — | |
| SCHEMBL4833922 | 0.77 | — | — | |
| SCHEMBL3564481 | 0.77 | — | — | |
| SCHEMBL4833880 | 0.77 | — | — | |
| SCHEMBL4837543 | 0.77 | — | — | |
| SCHEMBL4840348 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618207-B1 | Substituted pyridopyrimidines as antihypertensives | AMERICAN HOME PROD (US) | 1999-01-07 | — | — | EP | claimed |
| EP-0863143-A1 | Intermediates useful in the production of pyridopyrimidone angiotensin AII antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0618207-A1 | Substituted pyridopyrimidines as antihypertensives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-10-05 | — | — | EP | claimed |
| US-11555009-B2 | 2-(substituted benzene matrix) aromatic formate FTO inhibitor, preparation method therefor, and applications thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-01-17 | — | — | US | disclosed |
| CN-108524482-B | Use of 2- (substituted phenylamino) benzoic acid FTO inhibitors for treating leukemia | 中国科学院上海药物研究所 | 2022-11-25 | — | — | CN | disclosed |
| CN-114907267-A | Pharmaceutical composition for resisting tumor | 中国科学院上海药物研究所 | 2022-08-16 | — | — | CN | disclosed |
| US-20200079727-A1 | 2-(SUBSTITUTED BENZENE MATRIX) AROMATIC FORMATE FTO INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-03-12 | — | — | US | disclosed |
| EP-3270196-B1 | METHOD FOR MANUFACTURING A BANDPASS FILTER | FUJIFILM CORP (JP) | 2019-11-13 | — | — | EP | disclosed |
| CN-104069092-B | 2- (replacing phenylamino) benzoic acid and its ester type compound prepare the purposes of FTO inhibitor | 中国科学院上海药物研究所 | 2019-10-01 | — | — | CN | disclosed |
| CN-109310585-A | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108807180-A | Method for forming semiconductor device | 台湾积体电路制造股份有限公司 | 2018-11-13 | — | — | CN | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |
| CN-1057269-A | Peptide compounds and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-25 | — | — | CN | disclosed |
| EP-0457195-A2 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| EP-0315899-A2 | Thien-3-yl azo dyes | BASF Aktiengesellschaft (DE) | 1989-05-17 | — | — | EP | disclosed |
| CN-85104455-A | Novel tetrahydro-beta-carboline derivatives and process for preparing same | — | 1986-12-10 | — | — | CN | disclosed |
| EP-0008540-B1 | 2-ARYL-1,3-INDANDIONE DERIVATIVES AND COMPOSITIONS COMPRISING THEM FOR CONTROLLING ECTOPARASITIC ACARINA | UNION CARBIDE CORPORATION (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4394520-A | SKIN DISORDERS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-07-19 | — | — | US | disclosed |
| US-4204064-A | FOR TREATMENT OF SKIN OR SCALP | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4085217-A | DERIVATIVES OF CYSTEINE OR CYSTEAMINE | L'OREAL (FR) | 1978-04-18 | — | — | US | disclosed |