Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022670 | 0.84 | ALDH1A1 (0.57) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL457815 | 0.83 | EIF2AK2 (0.46) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL19002557 | 0.83 | L3MBTL1 (0.53) | EIF2AK2ALDH1A1KMT2AMEN1CCNA2 | |
| SCHEMBL19049511 | 0.79 | EIF2AK2 (0.44) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL18997277 | 0.79 | EIF2AK2 (0.44) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5640482 | 0.79 | EIF2AK2 (0.52) | EIF2AK2ALDH1A1LMNAKMT2AITGB3 | |
| SCHEMBL3559931 | 0.79 | ALDH1A1 (0.50) | EIF2AK2ALDH1A1LMNACMA1HPGD | |
| SCHEMBL2199529 | 0.78 | KMT2A (0.41) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL12068144 | 0.78 | EIF2AK2 (0.39) | EIF2AK2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8303472 | 0.77 | RPS6KA3 (0.49) | EIF2AK2ALDH1A1CMA1BCAT2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192733-A1 | SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192733-A1 | SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SARS1, ACE2, ACE | EIF2AK2 67/4885ALDH1A1 4373/4885LMNA 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.