⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537525 | 0.72 | — | — | |
| SCHEMBL2532418 | 0.59 | CYP19A1 (0.32) | — | |
| SCHEMBL74453 | 0.57 | — | — | |
| SCHEMBL2513229 | 0.57 | — | — | |
| SCHEMBL15028121 | 0.56 | LMNA (0.31) | — | |
| SCHEMBL9697494 | 0.55 | — | — | |
| SCHEMBL129682 | 0.55 | — | — | |
| SCHEMBL9619809 | 0.55 | — | — | |
| SCHEMBL7841816 | 0.53 | POLB (0.37) | — | |
| SCHEMBL12578966 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382972-A1 | Methods for preventing and treating neurodegenerative disorders | Boehringer Ingelheim International GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20100081625-A1 | METHODS FOR PREVENTING AND TREATING NEURODEGENERATIVE DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | US | disclosed |