Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678892 | 0.81 | NPC1 (0.47) | CYP19A1HTR2CAADATALDH1A1MAPT | |
| SCHEMBL21543007 | 0.81 | CYP19A1 (0.44) | CYP19A1HTR2CAADATALDH1A1MAPT | |
| SCHEMBL21543340 | 0.75 | SCD (0.45) | CYP19A1AADATEPHX2KLKB1ADORA3 | |
| SCHEMBL22346821 | 0.71 | SMN1; SMN2 (0.52) | HTR2CAADATALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6034971 | 0.71 | HTR2C (0.40) | CYP19A1HTR2CALDH1A1MAPTL3MBTL1 | |
| SCHEMBL21542778 | 0.70 | ALDH1A1 (0.42) | ALDH1A1KLKB1SCDSCD5DRD4 | |
| SCHEMBL6036214 | 0.70 | HTR2C (0.39) | CYP19A1HTR2CALDH1A1MAPTL3MBTL1 | |
| SCHEMBL31298608 | 0.69 | NPC1 (0.71) | CYP19A1ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL1231553 | 0.69 | CNR2 (0.46) | CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24705709 | 0.69 | KLKB1 (0.36) | CYP19A1AADATALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203055-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE | BETTA PHARMACEUTICALS CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203055-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE | VIP, CYP11B2, CYP11B1 | CYP19A1 9/4885HTR2C 4362/4885AADAT 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.