Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SETDB1 | Q15047 | 4/20 | 0.40 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18611254 | 0.79 | NPSR1 (0.41) | NPSR1ALOX15VHLKMT2AKDM4E | |
| SCHEMBL25097602 | 0.79 | NPSR1 (0.41) | NPSR1ALOX15VHLKMT2AHDAC1 | |
| SCHEMBL14590706 | 0.79 | NPSR1 (0.52) | NPSR1ALOX15SETDB1KMT2AKDM4E | |
| SCHEMBL13868069 | 0.78 | P2RX3 (0.34) | P2RX3P2RX2MAPTRAB9A | |
| SCHEMBL16131996 | 0.76 | NPSR1 (0.53) | NPSR1ALOX15SETDB1VHLMAPT | |
| SCHEMBL13865274 | 0.75 | L3MBTL1 (0.44) | KDM4E | |
| SCHEMBL13309400 | 0.75 | P2RX3 (0.39) | KMT2AKDM4EP2RX3P2RX2MAPT | |
| SCHEMBL3387105 | 0.72 | SETDB1 (0.47) | NPSR1SETDB1VHLPOLB | |
| SCHEMBL16136259 | 0.72 | KDM4E (0.45) | NPSR1ALOX15SETDB1VHLKMT2A | |
| SCHEMBL15750231 | 0.71 | SETDB1 (0.44) | NPSR1ALOX15SETDB1VHLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137329-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |