Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.34 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22147094 | 0.91 | KMT2A (0.41) | KMT2APTGS1PTGS2HPGDSMN1; SMN2 | |
| SCHEMBL20198075 | 0.88 | SMN1; SMN2 (0.39) | KMT2APTGS1PTGS2TPSAB1HPGD | |
| SCHEMBL22100721 | 0.87 | KMT2A (0.40) | KMT2APTGS1PTGS2TPSAB1HPGD | |
| SCHEMBL25681106 | 0.83 | SIRT2 (0.37) | KMT2APTGS1PTGS2ALDH1A1KDM4E | |
| SCHEMBL21185388 | 0.83 | KMT2A (0.39) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23867925 | 0.82 | FOLH1 (0.37) | KMT2APTGS1PTGS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17823174 | 0.82 | PTGS1 (0.40) | KMT2APTGS1PTGS2HPGDSMN1; SMN2 | |
| SCHEMBL17823173 | 0.82 | PTGS1 (0.40) | KMT2APTGS1PTGS2HPGDSMN1; SMN2 | |
| SCHEMBL23933301 | 0.81 | KMT2A (0.40) | KMT2APTGS1PTGS2HPGDSMN1; SMN2 | |
| SCHEMBL23933300 | 0.81 | KMT2A (0.40) | KMT2APTGS1PTGS2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |