Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563898 | 0.79 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL2568143 | 0.79 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL2571159 | 0.73 | HDAC1 (0.49) | HDAC1HDAC6HDAC8OPRM1L3MBTL1 | |
| SCHEMBL2569444 | 0.73 | HDAC3 (0.46) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL3288909 | 0.72 | HDAC1 (0.51) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL17144454 | 0.71 | HDAC1 (0.50) | HDAC1HDAC6HDAC8ACEOPRM1 | |
| SCHEMBL14177604 | 0.69 | HSD11B1 (0.55) | HDAC1HDAC6HDAC8OPRM1SIGMAR1 | |
| SCHEMBL2565333 | 0.69 | ACE (0.49) | HDAC1HDAC6HDAC8ACEHPGD | |
| SCHEMBL17144562 | 0.68 | HDAC1 (0.47) | HDAC1HDAC6HDAC8OPRM1SIGMAR1 | |
| SCHEMBL4260666 | 0.68 | HDAC1 (0.45) | HDAC1HDAC6HDAC8OPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626961-B1 | NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KOREA RES INST OF BIOSCIENCE (KR) | 2011-11-02 | — | — | EP | disclosed |