Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981845 | 0.86 | HCAR3 (0.55) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL25599234 | 0.85 | ALDH1A1 (0.49) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL2473868 | 0.85 | ALDH1A1 (0.46) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL8349171 | 0.84 | ALDH1A1 (0.45) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL25205988 | 0.84 | ALDH1A1 (0.53) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL20750204 | 0.84 | TDP1 (0.42) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL17261901 | 0.81 | HTT (0.50) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL29392110 | 0.81 | HTT (0.50) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL10612556 | 0.80 | MAPT (0.44) | HCAR3HTTMAPTALDH1A1KMT2A | |
| SCHEMBL28366340 | 0.77 | MAPT (0.43) | HCAR3HTTMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192844-A1 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192844-A1 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | CD2, CD47, KLK3 | HCAR3 402/4885HTT 900/4885MAPT 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.