Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566201 | 0.97 | CCKBR (0.40) | CCKBRF10ROCK2SIRT5SIRT1 | |
| SCHEMBL2567471 | 0.92 | F10 (0.36) | CCKBRF10ROCK2SIRT1SIRT2 | |
| SCHEMBL2572469 | 0.91 | CCKBR (0.39) | CCKBRF10ROCK2SIRT5SIRT1 | |
| SCHEMBL2572104 | 0.91 | CCKBR (0.38) | CCKBRF10ROCK2CA12CA1 | |
| SCHEMBL2572736 | 0.90 | CCKBR (0.38) | CCKBRF10ROCK2CA12CA1 | |
| SCHEMBL3382957 | 0.90 | F10 (0.44) | CCKBRF10ROCK2 | |
| SCHEMBL2567570 | 0.90 | CCKBR (0.37) | CCKBRF10ROCK2CA12CA1 | |
| SCHEMBL2566723 | 0.90 | CCKBR (0.37) | CCKBRF10ROCK2CA12CA1 | |
| SCHEMBL2573538 | 0.89 | CCKBR (0.38) | CCKBRF10ROCK2 | |
| SCHEMBL2574207 | 0.89 | CCKBR (0.38) | CCKBRF10ROCK2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |