Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 7/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569424 | 0.96 | CCKBR (0.39) | CCKBRALDH1A1KDM4EGAAF10 | |
| SCHEMBL2571105 | 0.93 | KDM4E (0.34) | CCKBRALDH1A1KDM4EGAAF10 | |
| SCHEMBL2567238 | 0.92 | CCKBR (0.38) | CCKBRALDH1A1F10ROCK2CA12 | |
| SCHEMBL2571203 | 0.90 | F10 (0.34) | CCKBRALDH1A1KDM4EGAAF10 | |
| SCHEMBL2568293 | 0.90 | CCKBR (0.40) | CCKBRF10ROCK2CA12CA1 | |
| SCHEMBL3380733 | 0.89 | CCKBR (0.37) | CCKBRALDH1A1F10ROCK2CA12 | |
| SCHEMBL2566201 | 0.89 | CCKBR (0.40) | CCKBRF10ROCK2 | |
| SCHEMBL3036552 | 0.88 | CCKBR (0.43) | CCKBRALDH1A1KDM4EGAAF10 | |
| SCHEMBL3382049 | 0.88 | CCKBR (0.35) | CCKBRALDH1A1KDM4EF10ROCK2 | |
| SCHEMBL2572469 | 0.85 | CCKBR (0.39) | CCKBRALDH1A1KDM4EF10ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |