Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900016 | 0.79 | GRM5 (0.34) | GRM5 | |
| SCHEMBL26967865 | 0.79 | MAPT (0.36) | GRM5 | |
| SCHEMBL22152282 | 0.77 | MAPT (0.31) | — | |
| SCHEMBL22017463 | 0.73 | ALDH1A1 (0.37) | GRM5 | |
| SCHEMBL18653072 | 0.72 | — | — | |
| SCHEMBL509506 | 0.71 | GRM5 (0.34) | GRM5 | |
| SCHEMBL25683005 | 0.70 | BRD4 (0.37) | GRM5 | |
| SCHEMBL26506118 | 0.70 | GRM5 (0.34) | GRM5 | |
| SCHEMBL9200910 | 0.69 | — | — | |
| SCHEMBL22216430 | 0.68 | GRM5 (0.33) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109751-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVE AND MEDICINAL USE THEREOF | 希格生科（深圳）有限公司 | 2023-06-22 | — | — | WO | disclosed |