Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25588902 | 0.87 | PIK3CD (0.34) | GRM5 | |
| SCHEMBL29105088 | 0.84 | SMN1; SMN2 (0.31) | GRM5 | |
| SCHEMBL22733316 | 0.83 | — | — | |
| SCHEMBL22733401 | 0.83 | — | — | |
| SCHEMBL22216430 | 0.78 | GRM5 (0.33) | GRM5CNR1 | |
| SCHEMBL22017463 | 0.75 | ALDH1A1 (0.37) | GRM5L3MBTL1MAPT | |
| SCHEMBL26506118 | 0.71 | GRM5 (0.34) | GRM5MAPT | |
| SCHEMBL25683000 | 0.71 | GRM5 (0.35) | GRM5 | |
| SCHEMBL9200910 | 0.70 | — | — | |
| SCHEMBL10094964 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| WO-2026099827-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | ALCON INC. (CH) | 2026-05-15 | — | — | WO | claimed |
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| EP-4713721-A1 | UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-03-10 | — | — | US | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-3759528-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| WO-2011075377-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011071790-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | NOVARTIS AG (CH) | 2011-06-16 | — | — | WO | claimed |
| US-20110140292-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | ALCON INC. (CH) | 2011-06-16 | — | — | US | claimed |
| US-20110133350-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | ALCON INC. (CH) | 2011-06-09 | — | — | US | claimed |
| WO-2011056761-A1 | A SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | NOVARTIS AG (CH) | 2011-05-12 | — | — | WO | claimed |
| US-20110102736-A1 | SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | ALCON INC. (CH) | 2011-05-05 | — | — | US | claimed |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
| US-5035884-A | Methylene pyrrolidone copolymers for contact lens and pharmaceutical preparations | WARNER-LAMBERT COMPANY (US) | 1991-07-30 | — | — | US | claimed |
| US-4931519-A | Copolymers from n-alkyl-3-alkenylene-2-pyrrolidone | WARNER-LAMBERT COMPANY (US) | 1990-06-05 | — | — | US | claimed |
| US-4851545-A | N-substituted-3-alkylene-2-pyrrolidone compounds | WARNER-LAMBERT COMPANY (US) | 1989-07-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | RAD51, ERCC1, LANCL2 | GRM5 2723/4885CNR1 607/4885NOTUM 3583/4885 |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | CRYZ, STRA6, PHOSPHO1 | GRM5 3731/4885CNR1 3995/4885NOTUM 435/4885 |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ATRIP, ATR, MACF1 | GRM5 1873/4885CNR1 4792/4885NOTUM 764/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | GRM5 2926/4885CNR1 4350/4885NOTUM 2517/4885 |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | CRYAB, CRYZ, CRYAA | GRM5 4056/4885CNR1 3711/4885NOTUM 2685/4885 |
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | GRM5 838/4885CNR1 4076/4885NOTUM 1118/4885 |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | CRYZ, CRYAB, CRYAA | GRM5 3693/4885CNR1 4111/4885NOTUM 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.