Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RGS4 | P49798 | 2/20 | 0.40 |
| ▸ | RGS8 | P57771 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25160404 | 0.86 | ALDH1A1 (0.43) | MAPTTP53ELANEF2CTSG | |
| SCHEMBL14889068 | 0.84 | MAPT (0.39) | MAPTTP53GAAMGLLSMN1; SMN2 | |
| SCHEMBL20644611 | 0.83 | MAPT (0.39) | MAPTTP53ELANEF2CTSG | |
| SCHEMBL17664675 | 0.75 | RGS4 (0.47) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL4623309 | 0.72 | MAPT (0.39) | MAPTTP53ELANEF2CTSG | |
| SCHEMBL17660251 | 0.70 | ELANE (0.41) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL25160112 | 0.68 | RGS4 (0.34) | MAPTELANEF2CTSGCMA1 | |
| SCHEMBL29819619 | 0.68 | GSK3A (0.44) | MAPTELANEF2CTSGCMA1 | |
| SCHEMBL25160199 | 0.68 | PPARD (0.48) | MAPTELANEF2CTSGCMA1 | |
| SCHEMBL17660383 | 0.66 | BTK (0.34) | MAPTTP53ELANEF2CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |