Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 5/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868253 | 1.00 | HPGD (0.47) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL1384803 | 1.00 | HPGD (0.47) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL3868250 | 1.00 | HPGD (0.47) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL13866886 | 1.00 | HPGD (0.47) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL3965258 | 0.93 | HPGD (0.42) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL1385240 | 0.92 | ITGB3 (0.51) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL2572450 | 0.92 | ITGB3 (0.51) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL3972336 | 0.91 | PIM1 (0.43) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL3972338 | 0.91 | PIM1 (0.43) | HPGDAKR1B1PIM1PIM2NPC1 | |
| SCHEMBL3965304 | 0.91 | REN (0.42) | HPGDAKR1B1PIM1PIM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583529-B1 | AMINO ACID PHENOXY ETHERS, THEIR PREPARATION AND USES | BEXEL PHARMACEUTICALS INC (US) | 2011-11-09 | — | — | EP | claimed |