Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25690615 | 0.92 | SCN9A (0.47) | CNR2HPGDSCHRM4NPC1RAB9A | |
| SCHEMBL25690434 | 0.92 | SCN9A (0.47) | CNR2HPGDSCHRM4NPC1RAB9A | |
| SCHEMBL25690685 | 0.92 | SCN9A (0.47) | CNR2HPGDSCHRM4NPC1RAB9A | |
| SCHEMBL25690421 | 0.90 | DPP4 (0.45) | CHRM4NPC1RAB9ADPP4 | |
| SCHEMBL25690689 | 0.85 | CD38 (0.48) | NPC1RAB9ADPP4 | |
| SCHEMBL25690609 | 0.85 | CNR2 (0.52) | CNR2BRD4HPGDSNPC1RAB9A | |
| SCHEMBL25690440 | 0.83 | CHRNB2 (0.45) | HDAC4HDAC6 | |
| SCHEMBL25690684 | 0.81 | CHRM5 (0.40) | BRD4HPGDSNPC1RAB9ASCN9A | |
| SCHEMBL25690606 | 0.81 | GRM5 (0.38) | CNR2NPC1RAB9ADPP4 | |
| SCHEMBL25690437 | 0.81 | CHRM5 (0.40) | BRD4HPGDSNPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |