Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25690684 | 1.00 | CHRM5 (0.40) | CHRM5BRD4HPGDSSCN9ASCN7A | |
| SCHEMBL25690606 | 0.89 | GRM5 (0.38) | GRM5HSD11B1DPP4CCNA2CDK2 | |
| SCHEMBL25690421 | 0.87 | DPP4 (0.45) | GRM5HSD11B1DPP4ALDH1A1CNR1 | |
| SCHEMBL25690427 | 0.84 | BRD4 (0.37) | BRD4SCN9AGRM5DPP4CCNA2 | |
| SCHEMBL25690611 | 0.84 | BRD4 (0.37) | BRD4SCN9AGRM5DPP4CCNA2 | |
| SCHEMBL25690689 | 0.82 | CD38 (0.48) | DPP4CNR1NPC1RAB9A | |
| SCHEMBL25690436 | 0.82 | ALDH1A1 (0.39) | GRM5HSD11B1DPP4ALDH1A1NPC1 | |
| SCHEMBL25690431 | 0.81 | SCN9A (0.43) | SCN9ASCN7AKCNH2SCN5AGRM5 | |
| SCHEMBL25690429 | 0.81 | CNR2 (0.48) | BRD4HPGDSSCN9ADPP4NPC1 | |
| SCHEMBL25690440 | 0.80 | CHRNB2 (0.45) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |