Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484062 | 0.91 | MEN1 (0.61) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL22652448 | 0.81 | CTSL (0.60) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL20201377 | 0.81 | CTSL (0.60) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL20069743 | 0.80 | CTSL (0.63) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL994466 | 0.80 | CTSL (0.63) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL358264 | 0.80 | CTSL (0.63) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL10274561 | 0.80 | CTSL (0.63) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL13801318 | 0.79 | DRD4 (0.66) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL24371203 | 0.78 | CTSL (0.60) | CTSLCTSBCTSKMEN1KMT2A | |
| SCHEMBL27553686 | 0.78 | CTSL (0.60) | CTSLCTSBCTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006956-A9 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2023105417-A1 | DANEGAPTIDE FORMULATION FOR APPLICATOIN IN THE EYE | BREYE THERAPEUTICS APS (DK) | 2023-06-15 | — | — | WO | disclosed |