Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562015 | 0.90 | CYP3A4 (0.36) | PDE4APDE4BPDE4CPDE4DPARG | |
| SCHEMBL28996689 | 0.75 | — | — | |
| SCHEMBL2562494 | 0.73 | CYP3A4 (0.37) | PDE4APDE4BPDE4CPDE4DPARG | |
| SCHEMBL27007022 | 0.71 | RELA (0.44) | MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL17424335 | 0.69 | — | — | |
| Sulfuric Acid SCHEMBL7119756 | 0.68 | LOX (0.67) | LOXLOXL3LOXL2MEN1KMT2A | |
| SCHEMBL2569040 | 0.68 | MEN1 (0.47) | LOXLOXL3LOXL2MEN1KMT2A | |
| 1,2-Dichloroethane SCHEMBL29125660 | 0.67 | — | — | |
| SCHEMBL339 | 0.67 | — | — | |
| SCHEMBL27565622 | 0.67 | LOX (1.00) | LOXLOXL3LOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |