Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.67 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.67 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339 | 0.82 | — | — | |
| Bicarbonate SCHEMBL28678945 | 0.80 | KMT2A (0.73) | LOXLOXL3LOXL2MEN1KMT2A | |
| Bicarbonate SCHEMBL909963 | 0.80 | — | — | |
| Sulfuric Acid SCHEMBL27605494 | 0.79 | CA5A (0.40) | LOXLOXL3LOXL2MEN1KMT2A | |
| Sulfuric Acid SCHEMBL73406 | 0.79 | — | — | |
| Sulfuric Acid SCHEMBL28163759 | 0.79 | CA5A (0.40) | LOXLOXL3LOXL2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2719729 | 0.78 | — | — | |
| Carbamic Acid SCHEMBL28684032 | 0.78 | — | — | |
| Oxalic Acid SCHEMBL11876639 | 0.78 | KMT2A (0.70) | LOXLOXL3LOXL2MEN1KMT2A | |
| Sulfuric Acid SCHEMBL5694300 | 0.75 | BLM (0.53) | MEN1KMT2ABLMLMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653488-B2 | Reacting a 3-aminopropionitrile with benzophenonecarboxylic acid; amidation | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-11-25 | — | — | US | claimed |
| US-6653488-B2 | Reacting a 3-aminopropionitrile with benzophenonecarboxylic acid; amidation | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-11-25 | — | — | US | disclosed |
| JP-2003055330-A | METHOD FOR STABILIZING 3-AMINOPROPIONITRILE | CENTRAL GLASS CO LTD | 2003-02-26 | — | — | JP | disclosed |
| EP-0030474-B1 | PROCESS FOR THE PRODUCTION OF DL-SERINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-01-19 | — | — | EP | disclosed |