Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25696366 | 0.89 | CES2 (0.32) | CES1CES2 | |
| SCHEMBL14611135 | 0.80 | — | — | |
| SCHEMBL19409889 | 0.76 | CES1 (0.46) | CES1CES2FAAHTP53SOAT1 | |
| SCHEMBL28419426 | 0.70 | CES2 (0.48) | CES1CES2FAAHTP53SOAT1 | |
| SCHEMBL15474220 | 0.69 | CES1 (0.48) | CES1CES2TP53MEN1KMT2A | |
| SCHEMBL14106691 | 0.69 | — | — | |
| SCHEMBL178873 | 0.69 | — | — | |
| SCHEMBL4201474 | 0.69 | — | — | |
| SCHEMBL160883 | 0.69 | — | — | |
| SCHEMBL11296708 | 0.68 | CES2 (0.50) | CES1CES2FAAHTP53SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111683-A1 | N4-HYDROXYCYTIDINE DERIVATIVES AND USE THEREOF AS ANTIVIRAL AGENT | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |