Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.30 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.30 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25696456 | 1.00 | CRBN (0.36) | CRBNDDB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3599475 | 0.88 | L3MBTL1 (0.38) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| SCHEMBL3599479 | 0.88 | L3MBTL1 (0.38) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| SCHEMBL2917208 | 0.88 | L3MBTL1 (0.38) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7740769 | 0.87 | ELANE (0.39) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| SCHEMBL22143927 | 0.81 | DDB1 (0.45) | CRBNDDB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL14294607 | 0.80 | CRBN (0.43) | CRBNDDB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3595531 | 0.80 | L3MBTL1 (0.40) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| SCHEMBL3595533 | 0.80 | L3MBTL1 (0.40) | CRBNDDB1ALDH1A1KMT2ATSHR | |
| SCHEMBL14294603 | 0.79 | MAP1LC3B (0.41) | CRBNDDB1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088477-A1 | MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE | 杭州和正医药有限公司 | 2023-05-25 | — | — | WO | disclosed |