Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TYMS | P04818 | 2/20 | 0.56 |
| ▸ | TK1 | P04183 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752755 | 1.00 | POLB (0.63) | POLBTYMSTK1 | |
| SCHEMBL24059268 | 0.90 | POLB (0.66) | POLBTYMSTK1 | |
| SCHEMBL25756120 | 0.89 | POLB (0.62) | POLBTYMSTK1 | |
| SCHEMBL25751494 | 0.89 | TK1 (0.52) | POLBTYMSTK1 | |
| SCHEMBL25751535 | 0.89 | TK1 (0.52) | POLBTYMSTK1 | |
| SCHEMBL25756126 | 0.88 | POLB (0.61) | POLBTYMSTK1 | |
| SCHEMBL21067874 | 0.85 | POLB (0.74) | POLBTYMSTK1 | |
| SCHEMBL19681260 | 0.84 | POLB (0.75) | POLBTYMSTK1 | |
| SCHEMBL9116326 | 0.84 | POLB (0.75) | POLBTYMSTK1 | |
| Thymidine Monophosphate SCHEMBL16092807 | 0.83 | POLB (0.80) | POLBTYMSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |