Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | POLD1 | P28340 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751494 | 1.00 | TK1 (0.52) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL25751533 | 0.90 | TK1 (0.57) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL25752755 | 0.89 | POLB (0.63) | TK1POLBTYMS | |
| SCHEMBL25696528 | 0.89 | POLB (0.63) | TK1POLBTYMS | |
| SCHEMBL25129239 | 0.84 | TK1 (0.56) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL25756120 | 0.79 | POLB (0.62) | TK1POLBTYMS | |
| SCHEMBL15236309 | 0.79 | TK1 (0.59) | TK1RNASE1 | |
| SCHEMBL16426201 | 0.79 | TK1 (0.59) | TK1RNASE1 | |
| SCHEMBL12360859 | 0.79 | TK1 (0.59) | TK1RNASE1 | |
| SCHEMBL24059268 | 0.79 | POLB (0.66) | TK1POLBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |