Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25696647 | 1.00 | PDE7A (0.43) | PDE7ACHRM4DPP4SCN9AABL1 | |
| SCHEMBL25698486 | 0.89 | CHRM4 (0.49) | CHRM4DPP4ABL1ALDH1A1CNR1 | |
| SCHEMBL25690688 | 0.87 | PDE7A (0.42) | PDE7ACHRM4DPP4SCN9APRKAA2 | |
| SCHEMBL25690439 | 0.87 | PDE7A (0.42) | PDE7ACHRM4DPP4SCN9APRKAA2 | |
| SCHEMBL27398490 | 0.76 | BRD4 (0.42) | CHRM4DPP4SCN9AABL1ALDH1A1 | |
| SCHEMBL25690427 | 0.75 | BRD4 (0.37) | PDE7ADPP4SCN9APRKAA2PARP1 | |
| SCHEMBL25690611 | 0.75 | BRD4 (0.37) | PDE7ADPP4SCN9APRKAA2PARP1 | |
| SCHEMBL25696639 | 0.75 | SCN9A (0.48) | CHRM4SCN9AABL1NPC1RAB9A | |
| SCHEMBL25236780 | 0.75 | ALDH1A1 (0.46) | CHRM4DPP4ALDH1A1CNR1HSD11B1 | |
| SCHEMBL25690421 | 0.75 | DPP4 (0.45) | CHRM4DPP4ALDH1A1CNR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |