Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599617 | 0.94 | ALDH1A1 (0.50) | ALDH1A1DPP4KMT2ACYP1A2CYP2C19 | |
| SCHEMBL25698486 | 0.84 | CHRM4 (0.49) | ALDH1A1DPP4CYP1A2CYP2C19CNR1 | |
| SCHEMBL25690421 | 0.81 | DPP4 (0.45) | ALDH1A1DPP4KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22912737 | 0.78 | RAB9A (0.46) | ALDH1A1KMT2ACNR1NPC1RAB9A | |
| SCHEMBL25690689 | 0.77 | CD38 (0.48) | DPP4KMT2ACNR1NPC1RAB9A | |
| SCHEMBL25912411 | 0.75 | ABL1 (0.49) | ALDH1A1DPP4CNR1HSD11B1CHRM4 | |
| SCHEMBL25696643 | 0.75 | PDE7A (0.43) | ALDH1A1DPP4CYP1A2CYP2C19CNR1 | |
| SCHEMBL25696647 | 0.75 | PDE7A (0.43) | ALDH1A1DPP4CYP1A2CYP2C19CNR1 | |
| SCHEMBL153746 | 0.74 | RAB9A (0.41) | ALDH1A1DPP4KMT2ANPC1RAB9A | |
| SCHEMBL24156520 | 0.74 | CNR1 (0.44) | ALDH1A1KMT2AMEN1CNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163022-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| WO-2024227026-A1 | HETEROCYCLIC COMPOUNDS AS PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| EP-4452963-A1 | PARP1 INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118696036-A | PARP1 inhibitors | 突触活化疗法股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163022-A1 | PARP1 INHIBITORS | PARP1, PARP11, PARP12 | ALDH1A1 2238/4885DPP4 2680/4885KMT2A 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.