Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 13/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569655 | 0.85 | HPGD (0.41) | NPC1HTTRAB9ASMN1; SMN2ROCK2 | |
| SCHEMBL2565731 | 0.83 | POLB (0.45) | TP53HTTSMN1; SMN2 | |
| SCHEMBL2571876 | 0.82 | ROCK2 (0.48) | NPC1TP53RAB9ATMPRSS2ROCK2 | |
| SCHEMBL3036150 | 0.80 | F10 (0.46) | TMPRSS2ROCK2 | |
| SCHEMBL2567344 | 0.80 | NPC1 (0.48) | NPC1TP53GAANFKB1HTT | |
| SCHEMBL2567223 | 0.78 | HRH3 (0.47) | NPC1RAB9ATMPRSS2ROCK2CYP3A4 | |
| SCHEMBL2570020 | 0.78 | KDM4E (0.48) | NPC1HTTRAB9ATMPRSS2ROCK2 | |
| SCHEMBL2578923 | 0.78 | KDM4E (0.40) | HTTSMN1; SMN2ROCK2CYP3A4 | |
| SCHEMBL2570332 | 0.78 | KDM4E (0.47) | NPC1HTTRAB9ASMN1; SMN2TMPRSS2 | |
| SCHEMBL6295065 | 0.77 | NPC1 (0.66) | NPC1TP53GAANFKB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | claimed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | claimed |