Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569706 | 0.85 | NPC1 (0.50) | HTTSMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL2565731 | 0.85 | POLB (0.45) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2571876 | 0.82 | ROCK2 (0.48) | ALDH1A1KMT2ANPC1RAB9AROCK2 | |
| SCHEMBL2578923 | 0.82 | KDM4E (0.40) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2570332 | 0.82 | KDM4E (0.47) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2567442 | 0.81 | HDAC8 (0.47) | SMN1; SMN2NPC1RAB9AROCK2HDAC8 | |
| SCHEMBL2573167 | 0.81 | ALOX15 (0.44) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2567550 | 0.80 | POLB (0.46) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2563694 | 0.80 | ALOX15 (0.43) | HPGDALOX15HTTMAPK1SMN1; SMN2 | |
| SCHEMBL2570020 | 0.80 | KDM4E (0.48) | HPGDALOX15HTTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | claimed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | claimed |