Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697138 | 0.87 | CA12 (0.52) | MAPTMAOBPOLBTP53ALDH1A1 | |
| SCHEMBL25697270 | 0.77 | CA12 (0.56) | MAPTMAOBPOLBTP53ALDH1A1 | |
| SCHEMBL25697110 | 0.74 | MAPT (0.68) | MAPTMAOBPOLBTHRBTP53 | |
| SCHEMBL25697098 | 0.73 | GPR35 (0.59) | MAPTMAOBPOLBMAOAALDH1A1 | |
| SCHEMBL30425825 | 0.73 | MAOB (0.56) | MAPTMAOBTP53MAOAALDH1A1 | |
| SCHEMBL2031480 | 0.73 | KMT2A (0.74) | MAPTMAOBPOLBMAOAALDH1A1 | |
| SCHEMBL25697207 | 0.72 | MAOB (0.63) | MAPTMAOBTP53MAOAALDH1A1 | |
| SCHEMBL9319364 | 0.72 | MAOB (0.65) | MAPTMAOBPOLBTP53MAOA | |
| SCHEMBL1406760 | 0.72 | MAOB (0.62) | MAPTMAOBPOLBMAOAALDH1A1 | |
| SCHEMBL30425189 | 0.71 | ALDH1A1 (0.39) | MAPTPOLBTHRBTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094734-A1 | LIGANDS SPECIFICALLY TARGETING VESICULAR GLUTAMATE TRANSPORTERS FOR SUPER-RESOLUTION IMAGING | Sorbonne Université (FR) | 2023-06-01 | — | — | WO | disclosed |