Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25696459 | 0.86 | MAPK1 (0.48) | MAPK1MAPK14EGFRNPC1RAB9A | |
| SCHEMBL25700511 | 0.85 | CYP1A2 (0.41) | MAPK1MAPK14EGFRRPS6KA3TRPA1 | |
| SCHEMBL25696601 | 0.85 | TNKS (0.46) | TNKSTNKS2PIK3CDPIK3CAMTOR | |
| SCHEMBL20290060 | 0.85 | JAK1 (0.44) | MAPK1MAPK14EGFRRPS6KA3KDR | |
| SCHEMBL25696885 | 0.83 | MAPK1 (0.53) | MAPK1ALDH1A1PKMKDM4ENPC1 | |
| SCHEMBL25697037 | 0.83 | CCNT1 (0.38) | MAPK1MAPK14EGFRCSNK1DMAPK11 | |
| SCHEMBL20289959 | 0.81 | JAK1 (0.41) | MAPK1MAPK14PIK3CDPIK3CASYK | |
| SCHEMBL24642439 | 0.80 | PRKCI (0.33) | MAPK1MAPK14EGFRSYKKDR | |
| SCHEMBL25696739 | 0.80 | NPC1 (0.49) | MAPK1MAPK14EGFRALDH1A1PKM | |
| SCHEMBL24642489 | 0.79 | CHEK2 (0.47) | MAPK1ALDH1A1PKMKDM4ETNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023115327-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | 中国药科大学 | 2023-06-29 | — | — | WO | disclosed |