Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GPX4 | P36969 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189175 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2189172 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2190798 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL7397962 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2190802 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL22622465 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL22961947 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL1832185 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL1832187 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL23823914 | 0.79 | HCAR2 (0.48) | ALDH1A1HTTMAPTHCAR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081840-A1 | KRAS G12C INHIBITORS | FRONTIER MEDICINES CORPORATION (US) | 2023-05-11 | — | — | WO | disclosed |