Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GPX4 | P36969 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698382 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HTTMAPTKDM4EHPGD | |
| SCHEMBL23823410 | 0.82 | HCAR2 (0.45) | ALDH1A1HTTMAPTHPGDKEAP1 | |
| SCHEMBL2189175 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTKDM4EKEAP1 | |
| SCHEMBL2189172 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTKDM4EKEAP1 | |
| Acrylic Acid Methyl Ester SCHEMBL1592109 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTKDM4EHPGD | |
| SCHEMBL26699141 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2RAB9A | |
| SCHEMBL2609692 | 0.78 | L3MBTL1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2RAB9A | |
| SCHEMBL2190802 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTKDM4EHPGD | |
| SCHEMBL2190798 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTKDM4EHPGD | |
| SCHEMBL27322475 | 0.78 | RAB9A (0.46) | ALDH1A1HTTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |