Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052525 | 0.75 | CA1 (0.55) | ALDH1A1TRPA1TDP1BACE1CA1 | |
| SCHEMBL25698912 | 0.72 | CA1 (0.42) | ALKALDH1A1TRPA1TDP1BACE1 | |
| SCHEMBL21052584 | 0.70 | BCHE (0.47) | MAOAMAOBCES2ALDH1A1SRD5A1 | |
| SCHEMBL31597656 | 0.69 | SRD5A1 (0.40) | MAOAMAOBCES2ALDH1A1TDP1 | |
| SCHEMBL17016640 | 0.69 | ALDH1A1 (0.34) | ALKALDH1A1SRD5A1BACE1 | |
| SCHEMBL3994729 | 0.69 | L3MBTL1 (0.50) | MAOAMAOBALDH1A1BACE1CA1 | |
| SCHEMBL21052518 | 0.68 | PBRM1 (0.53) | MAOAMAOBALDH1A1SRD5A1 | |
| SCHEMBL3297666 | 0.68 | ALDH1A1 (0.46) | MAOAMAOBALDH1A1TRPA1TDP1 | |
| SCHEMBL2867311 | 0.68 | ALDH1A1 (0.46) | MAOAMAOBCES2ALDH1A1TRPA1 | |
| SCHEMBL21052522 | 0.67 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |