Mezepine

Mezepine

SCHEMBL38660320

CNCCCN1Cc2ccccc2Cc2ccccc21

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 17/20 0.55
SLC6A4 P31645 6/20 0.55
HTR2A P28223 3/20 0.55
HRH1 P35367 3/20 0.55
CYP3A4 P08684 2/20 0.55
SLC22A2 O15244 1/20 0.55
SLC22A1 O15245 1/20 0.55
SLC22A3 O75751 1/20 0.55
CYP1A2 P05177 1/20 0.55
CHRM2 P08172 1/20 0.55
CYP2D6 P10635 1/20 0.55
CHRM1 P11229 1/20 0.55
DRD2 P14416 1/20 0.55
ADRA2B P18089 1/20 0.55
ADRA2C P18825 1/20 0.55
NFKB1 P19838 1/20 0.55
CHRM3 P20309 1/20 0.55
HTR2C P28335 1/20 0.55
MAPK1 P28482 1/20 0.55
ADRA1A P35348 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mezepine SCHEMBL2110147 1.00 SLC6A2 (0.55) SLC6A2SLC6A4HTR2AHRH1CYP3A4
SCHEMBL7843815 0.80 ALDH1A1 (0.41) SLC6A2SLC6A4HTR2AHRH1CYP3A4
SCHEMBL25699276 0.79 SLC6A2 (0.52) SLC6A2SLC6A4HTR2AHRH1CYP3A4
Prazepine SCHEMBL2109939 0.79 HRH1 (0.55) SLC6A2SLC6A4HTR2AHRH1CYP3A4
SCHEMBL20476301 0.75 CYP1A2 (0.58) SLC6A2SLC6A4HTR2AHRH1CYP3A4
SCHEMBL11476563 0.74 SLC6A2 (0.50) SLC6A2SLC6A4HTR2AHRH1CYP3A4
Desipramine SCHEMBL29379525 0.71 SLC6A4 (1.00) SLC6A2SLC6A4HTR2AHRH1CYP3A4
Desipramine SCHEMBL34384 0.71 SLC6A4 (1.00) SLC6A2SLC6A4HTR2AHRH1CYP3A4
Desipramine SCHEMBL5072939 0.71 SLC6A4 (1.00) SLC6A2SLC6A4HTR2AHRH1CYP3A4
SCHEMBL11993891 0.71 NAMPT (0.56) CYP3A4CYP1A2CYP2D6DRD2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037805-A Fire extinguishing expansion adhesive tape for secondary battery and preparation method thereof 东莞市方恩电子材料科技有限公司 2026-05-15 CN disclosed