Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461563 | 0.76 | MAPT (0.35) | HTT | |
| SCHEMBL20644490 | 0.74 | PDE2A (0.41) | PDE2AHTTESR1ESR2 | |
| SCHEMBL20153631 | 0.73 | CES2 (0.48) | PDE2A | |
| SCHEMBL20768664 | 0.72 | ANPEP (0.52) | — | |
| SCHEMBL19331703 | 0.71 | DPP4 (0.51) | HTTDPP4 | |
| SCHEMBL23646682 | 0.70 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL2017897 | 0.70 | CES2 (0.42) | — | |
| SCHEMBL23646685 | 0.70 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL23646588 | 0.70 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL25248787 | 0.70 | CHRNA7 (0.39) | PDE2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |