SCHEMBL8461563

SCHEMBL8461563

C=C(c1ccc(C(=C)C(C)C)cc1)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
GFER P55789 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
KDM4E B2RXH2 1/20 0.34
DBH P09172 1/20 0.34
GAA P10253 1/20 0.34
RECQL P46063 1/20 0.34
LMNA P02545 1/20 0.34
XBP1 P17861 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ELANE P08246 1/20 0.33
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9626474 0.89 MAPT (0.52) MAPTHTTGFERHSD17B10GPR55
SCHEMBL12981369 0.89 ALDH1A1 (0.44) HTTKMT2AMEN1GAALMNA
SCHEMBL2017897 0.87 CES2 (0.42) KMT2ACA1CA2
SCHEMBL1965137 0.87 TPMT (0.41) CA1CA2
SCHEMBL2012718 0.87 CES2 (0.42) MAPTHTTLMNAATMCA1
SCHEMBL693987 0.86 SMN1; SMN2 (0.50) MAPTHTTHSD17B10KMT2AMEN1
SCHEMBL14530150 0.85 TSHR (0.55) HSD17B10KMT2ASMN1; SMN2CA12CA1
SCHEMBL19675411 0.85 MEN1 (0.55) MAPTHTTGFERHSD17B10KMT2A
Hydrogen Sulfide SCHEMBL29028321 0.84 SMN1; SMN2 (0.48) MAPTHTTHSD17B10KMT2AMEN1
SCHEMBL24826669 0.83 ALDH1A1 (0.48) LMNAATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP claimed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US claimed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP claimed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP claimed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP claimed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US claimed
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP disclosed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US disclosed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP disclosed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP disclosed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP disclosed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US disclosed
EP-0122213-B1 PROCESS FOR MAKING POLYMERIC COMPOUNDS PREPARED FROM DIPHENYLAMINE AND DIALKYLALKENYLBENZENE OR DIHYDROXYALKYLBENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-03-22 EP disclosed
US-4537952-A Polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-27 US disclosed
EP-0122865-A1 Polymers with polymeric antioxidants prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-24 EP disclosed
EP-0122213-A1 Process for making polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-17 EP disclosed
EP-0117831-A1 Stabilized polyester compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-09-05 EP disclosed
US-4463170-A OXIDATION RESISTANCE STABILIZERS FOR POLYAMINES, POLYPHENYL RESINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-07-31 US disclosed
US-4417017-A Polymeric antioxidants prepared from diphenyalmine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-22 US disclosed
US-4414348-A POLYMERIC DIPHENYLAMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-08 US disclosed