Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 10/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244785 | 1.00 | HTR6 (0.38) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL30480400 | 1.00 | HTR6 (0.38) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL25283307 | 1.00 | HTR6 (0.38) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL25240038 | 0.88 | HTR6 (0.43) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL25284995 | 0.88 | HTR6 (0.43) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL29460624 | 0.88 | HTR6 (0.43) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL2272937 | 0.88 | HTR6 (0.43) | HTR6BCHEJAK1USP30JAK2 | |
| SCHEMBL2284399 | 0.86 | JAK1 (0.47) | HTR6BCHEJAK1JAK2TYK2 | |
| SCHEMBL2224575 | 0.86 | HTR6 (0.46) | HTR6BCHEJAK1JAK2TYK2 | |
| SCHEMBL2225830 | 0.83 | HTR6 (0.43) | HTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115327-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | 中国药科大学 | 2023-06-29 | — | — | WO | disclosed |