SCHEMBL257005

SCHEMBL257005

Nc1ccc2oc3ccccc3c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
KMT2A Q03164 5/20 1.00
NPC1 O15118 5/20 1.00
RAB9A P51151 5/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
ALDH1A1 P00352 5/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 4/20 1.00
MEN1 O00255 4/20 1.00
MAPK1 P28482 1/20 0.67
GFER P55789 1/20 0.61
AHR P35869 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
NQO1 P15559 1/20 0.48
MAOA P21397 3/20 0.46
HSD17B10 Q99714 2/20 0.46
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22271477 0.89 RAB9A (0.79) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL4760425 0.89 NPC1 (0.78) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL30340803 0.89 NPC1 (0.78) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL14174147 0.88 MAPT (0.89) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL31261599 0.87 MAPT (0.96) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL483639 0.87 MAPT (0.96) MAPTKMT2ANPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL11439943 0.85 MAPT (1.00) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL136810 0.84 KMT2A (0.73) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL29789019 0.84 NPC1 (0.72) MAPTKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL21585336 0.84 RAB9A (0.81) MAPTKMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4244910-B1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2024-12-11 EP claimed
CN-117143085-A ABS heat-resistant modifier, intermediate, high-temperature-resistant ABS material and preparation method 四川轻化工大学 2023-12-01 CN claimed
EP-4263544-B1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE EMITTERS IN OLEDS UDC IRELAND LTD (IE) 2026-05-13 EP disclosed
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-12527219-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-01-13 US disclosed
EP-4676208-A2 NITROGEN-CONTAINING HETERO-AROMATICS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2026-01-07 EP disclosed
EP-4379007-B1 INK COMPOSITION, ORGANIC MATERIAL LAYER COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2025-11-26 EP disclosed
US-12435098-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2025-10-07 US disclosed
EP-4263746-B1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2025-10-01 EP disclosed
US-4016152-A SUITABLE FOR DYEING POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3998802-A POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES BASF AKTIENGESELLSCHAFT (DT) 1976-12-21 US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435098-B2 Heterocyclic compound and organic light-emitting device comprising same CRKL, AHR, ATXN2L MAPT 4566/4885KMT2A 2906/4885NPC1 3909/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 MAPT 1607/4885KMT2A 880/4885NPC1 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.