SCHEMBL25701

SCHEMBL25701

CCCOCC(=O)Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
KDM4E B2RXH2 2/20 0.63
CYP1A2 P05177 2/20 0.63
HPGD P15428 6/20 0.57
MAPT P10636 5/20 0.57
ALOX12 P18054 1/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 1/20 0.57
NOTUM Q6P988 1/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
GAA P10253 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
KLK7 P49862 1/20 0.51
NPC1 O15118 1/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19500965 0.94 ALDH1A1 (0.57) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL17183962 0.90 ALDH1A1 (0.60) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL8654103 0.89 ALDH1A1 (0.58) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL19501254 0.87 KMT2A (0.52) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL3667956 0.86 KMT2A (0.69) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL9125307 0.85 ALDH1A1 (0.65) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL4696809 0.85 NAMPT (0.65) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL11420601 0.85 MAPT (0.61) ALDH1A1CYP1A2HPGDMAPTHTT
SCHEMBL3364875 0.84 KDM4E (0.56) ALDH1A1KDM4ECYP1A2HPGDMAPT
SCHEMBL9125155 0.83 ALDH1A1 (0.55) ALDH1A1KDM4ECYP1A2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102250012-B Process for preparing benzimidazole insectifuge oxibendazole JIANGSU BAOZONG BAODA PHARMACEUTICAL CO LTD 2012-12-19 CN claimed
CN-102250012-A Process for preparing benzimidazole insectifuge oxibendazole JIANGSU BAOZONG BAODA PHARMACEUTICAL CO LTD 2011-11-23 CN claimed
CN-1829510-A Dispersible formulation of an anti-inflammatory agent PHARMACIA & UPJOHN CO LTD (US) 2006-09-06 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-4210606-B1 MEDICAL DEVICE INCLUDING EXPANDABLE MUSCLE POLYMER BARD PERIPHERAL VASCULAR INC (US) 2024-05-01 EP disclosed
EP-3970643-B1 SCORING BALLOON WITH TRANSLATING SCORING WIRES BARD INC C R (US) 2024-04-17 EP disclosed
CN-115996686-B Medical device comprising expandable muscle polymer 巴德外周血管股份有限公司 2024-03-22 CN disclosed
US-11918447-B2 Systems, methods and devices relating to implantable supportive slings BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-03-05 US disclosed
US-11883272-B2 Tension-adjustable surgical sling assembly BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-01-30 US disclosed
US-20230389955-A1 Scoring Balloon With Translating Scoring Wires BARD INC C R (US) 2023-12-07 US disclosed
US-11771457-B2 Scoring balloon with translating scoring wires C.R. BARD, INC. (US) 2023-10-03 US disclosed
EP-1021204-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 2000-07-26 EP disclosed
US-6024976-A TRANSDERMAL DRUG DELIVERY WITH PRESSURE SENSITIVE ADHESIVE COMPOSITION OF POLYVINYLPYRROLIDONE WITH DRUG IN MULTILAYER PATCH NOVEN PHARMACEUTICALS, INC. (US) 2000-02-15 US disclosed
WO-1999015210-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1999-04-01 WO disclosed
US-5719197-A DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 1998-02-17 US disclosed
US-5656286-A BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE NOVEN PHARMACEUTICALS, INC. (US) 1997-08-12 US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed