Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654103 | 0.90 | ALDH1A1 (0.58) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL8712017 | 0.90 | KDM4E (0.54) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL17183962 | 0.88 | ALDH1A1 (0.60) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL18660223 | 0.88 | MAPT (0.58) | KDM4EALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL9125307 | 0.87 | ALDH1A1 (0.65) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL31666104 | 0.85 | SOAT2 (0.66) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL6706649 | 0.84 | KDM4E (0.49) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL27967069 | 0.84 | ALDH1A1 (0.55) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL25701 | 0.84 | ALDH1A1 (0.63) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL9125155 | 0.84 | ALDH1A1 (0.55) | KDM4ECYP1A2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | claimed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | KDM4E 192/4885CYP1A2 588/4885ALDH1A1 2240/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | KDM4E 861/4885CYP1A2 1154/4885ALDH1A1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.