SCHEMBL25702142

SCHEMBL25702142

CP(C)(=O)Oc1cc(OP(C)(C)=O)cc(OP(=O)(O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.76
INPP5A Q14642 5/20 0.76
SRC P12931 4/20 0.48
INPP5B P32019 1/20 0.48
BLM P54132 1/20 0.42
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AKT1 P31749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677217 0.87 INPPL1 (0.52) INPPL1INPP5AINPP5BALDH1A1CYP3A4
SCHEMBL4186085 0.87 INPPL1 (1.00) INPPL1INPP5ASRCINPP5BBLM
SCHEMBL21443850 0.86 INPPL1 (0.76) INPPL1INPP5ASRCINPP5BBLM
SCHEMBL27799416 0.81 INPPL1 (0.76) INPPL1INPP5ASRCINPP5BBLM
SCHEMBL15033097 0.77 INPPL1 (0.44) INPPL1INPP5AINPP5BALDH1A1CYP3A4
SCHEMBL7159151 0.76 INPPL1 (0.68) INPPL1INPP5ASRCINPP5BBLM
SCHEMBL20012157 0.76 INPPL1 (0.76) INPPL1INPP5ASRCINPP5BBLM
SCHEMBL13085852 0.76 INPPL1 (0.43) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL14282633 0.76 INPPL1 (0.43) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL14732755 0.74 INPPL1 (0.65) INPPL1INPP5ASRCINPP5BBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194509-A1 POLYCARBONATE COMPOSITIONS SHPP Global Technologies B.V. (NL) 2023-06-14 EP disclosed