SCHEMBL677217

SCHEMBL677217

CP(C)(=O)Oc1cc(OP(C)(C)=O)cc(OP(C)(C)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 6/20 0.52
INPP5A Q14642 4/20 0.52
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
INPP5B P32019 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HCRTR1 O43613 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25702142 0.87 INPPL1 (0.76) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL7764936 0.84 HCRTR1 (0.46) INPPL1INPP5ATDP1MEN1KMT2A
SCHEMBL15033097 0.83 INPPL1 (0.44) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL13577685 0.83 INPPL1 (0.39) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL14282633 0.82 INPPL1 (0.43) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL13085852 0.82 INPPL1 (0.43) INPPL1INPP5AALDH1A1CYP3A4TSHR
SCHEMBL13445961 0.81 CYP3A4 (0.52) CYP3A4TSHRTDP1MEN1KMT2A
SCHEMBL676524 0.75 SRC (0.58) TDP1MEN1KMT2A
SCHEMBL5489158 0.73 TSHR (0.70) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL5486829 0.71 ACHE (0.54) ALDH1A1CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912863-B2 Thermoplastic composition for laser direct structuring MEP EUROPE B.V. (NL) 2024-02-27 US disclosed
US-11806970-B2 Multilayer sheets including polyphenylene and polypropylene and methods of making the same (as amended) SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-07 US disclosed
US-20230340258-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING MEP EUROPE B.V. (NL) 2023-10-26 US disclosed
US-11713394-B2 Sheets including polyphenylene and an aryl salicylate and methods of making the same SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2023-08-01 US disclosed
US-20230174778-A1 POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-06-08 US disclosed
US-10017641-B2 Compatibilized compositions, articles formed therefrom, and methods of manufacture thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-10 US disclosed
US-9994709-B2 Thermoplastic compositions having low smoke, methods of their manufacture, and uses thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-12 US disclosed
US-9957351-B2 Polycarbonate compositions having enhanced optical properties, methods of making and articles comprising the polycarbonate compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-05-01 US disclosed
US-20180066135-A1 FLAME RETARDANT COMPOSITION, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-03-08 US disclosed
US-9896581-B2 Compositions and articles of manufacture containing branched polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-02-20 US disclosed
US-20070072960-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070072961-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070060716-A1 Fatigue resistant thermoplastic composition, method of making, and articles formed therefrom CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-15 US disclosed
US-20070049702-A1 High flow polyester composition, method of manufacture, and uses thereof SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-03-01 US disclosed
US-20070049706-A1 Low smoke polycarbonate composition, method of manufacture and product made therefrom CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-01 US disclosed
US-20070049701-A1 High flow polyester composition, method of manufacture, and uses thereof SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-03-01 US disclosed
US-20070048527-A1 The first layer contains a first composition that contains polycarbonate, polycarbonate-polysiloxane copolymer, impact modifier and polyetherimide; sheet, film; low smoke generation upon burning, impact resistance, flame retardance; molding SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-01 US disclosed
US-20070027268-A1 Reaction product obtained by melt blending two aromatic polyester-polycarbonates and a transesterification catalyst that has a haze of less than 1.0% GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-20070010635-A1 Low gloss thermoplastic composition, method of making, and articles formed therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-01-11 US disclosed
US-20070010618-A1 Low gloss thermoplastic composition, method of making, and articles formed therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-01-11 US disclosed