SCHEMBL4186085

SCHEMBL4186085

O=P(O)(O)Oc1cc(OP(=O)(O)O)cc(OP(=O)(O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 12/20 1.00
INPP5A Q14642 6/20 1.00
INPP5B P32019 2/20 0.60
SRC P12931 3/20 0.59
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
AKT1 P31749 1/20 0.46
BLM P54132 1/20 0.45
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27799416 0.87 INPPL1 (0.76) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL21443850 0.87 INPPL1 (0.76) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL20012157 0.87 INPPL1 (0.76) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL25702142 0.87 INPPL1 (0.76) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL4454764 0.84 INPPL1 (0.71) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL130697 0.84 INPPL1 (0.71) INPPL1INPP5AINPP5BSRCCA1
Phosphoric Acid SCHEMBL28992406 0.82 INPPL1 (0.68) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL29427946 0.82 INPPL1 (0.68) INPPL1INPP5AINPP5BSRCCA1
SCHEMBL7159151 0.82 INPPL1 (0.68) INPPL1INPP5AINPP5BSRCBLM
SCHEMBL11520191 0.82 INPPL1 (0.68) INPPL1INPP5AINPP5BSRCCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US claimed
JP-2008545385-A 2008-12-18 JP claimed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP claimed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO claimed
CN-117222705-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-12-12 CN disclosed
CN-117178003-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-12-05 CN disclosed
CN-117120494-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-11-24 CN disclosed
CN-117098787-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-11-21 CN disclosed
WO-2023131909-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V (NL) 2023-07-13 WO disclosed
US-20230067710-A1 TRANSPARENT, FLAME-RETARDANT HIGH-HEAT POLYCARBONATE COMPOSITIONS FOR THIN WALL APPLICATIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-03-02 US disclosed
US-20220389223-A1 THERMOPLASTIC COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-08 US disclosed
CN-114638513-A Radioactive waste solidification treatment evaluation method and alternative nuclide feasibility evaluation method 中广核研究院有限公司 2022-06-17 CN disclosed
US-9688842-B2 Thermoplastic polycarbonate copolymer compositions, methods of their manufacture, and articles thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-27 US disclosed
US-9650496-B2 Interior aircraft components and methods of manufacture SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-05-16 US disclosed
US-20160266129-A1 Phosphoinositide (4,5) Bisphosphate as a Diagnostic Tool and Target for Cancer Treatment JANETOPOULOS CHRISTOPHER (US) 2016-09-15 US disclosed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA INPPL1 40/4885INPP5A 15/4885INPP5B 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.