Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831928 | 0.83 | SIGMAR1 (0.38) | SMN1; SMN2HSD11B1MEN1TSHRHTT | |
| SCHEMBL18346708 | 0.83 | SIGMAR1 (0.38) | SMN1; SMN2HSD11B1MEN1TSHRHTT | |
| SCHEMBL21064697 | 0.83 | SIGMAR1 (0.38) | SMN1; SMN2HSD11B1MEN1TSHRHTT | |
| SCHEMBL15893910 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2HSD11B1EPHX1EPHX2CHRM1 | |
| SCHEMBL15896433 | 0.80 | HPGDS (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14436404 | 0.80 | — | — | |
| SCHEMBL17464820 | 0.80 | — | — | |
| SCHEMBL18478124 | 0.80 | — | — | |
| SCHEMBL3436833 | 0.71 | — | — | |
| SCHEMBL419842 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107606-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-15 | — | — | WO | disclosed |