Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.65 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.65 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | CES2 | O00748 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | CES1 | P23141 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.65 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone Iia SCHEMBL2026738 | 0.79 | EED (1.00) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL29538928 | 0.75 | EED (0.84) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL16023777 | 0.75 | EED (0.84) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| Przewaquinone A SCHEMBL16152272 | 0.73 | IDO1 (1.00) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL25704222 | 0.70 | MEN1 (0.43) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL29539317 | 0.70 | IDO1 (0.77) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL16152326 | 0.70 | EED (0.78) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL20458614 | 0.69 | CES1 (0.60) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| SCHEMBL3718424 | 0.68 | EED (0.58) | EEDSUZ12EZH2MEN1ALDH1A1 | |
| Tanshinone Iib SCHEMBL14417728 | 0.67 | EED (1.00) | EEDSUZ12EZH2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180034-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING NAPHTHOQUINONE-BASED COMPOUND AND IMMUNE CHECKPOINT INHIBITOR AS ACTIVE INGREDIENTS | NADIANBIO Ltd. (KR) | 2023-05-17 | — | — | EP | disclosed |