Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570533 | 0.82 | MEN1 (0.39) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL14955126 | 0.77 | MEN1 (0.49) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL2575493 | 0.76 | MEN1 (0.48) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL16360371 | 0.69 | TYMP (0.39) | TYMPTK1PDE9A | |
| SCHEMBL29154414 | 0.69 | MEN1 (0.48) | MEN1TSHRKMT2ATK1 | |
| SCHEMBL29154417 | 0.69 | MEN1 (0.48) | MEN1TSHRKMT2ATK1 | |
| SCHEMBL27041198 | 0.68 | HPRT1 (0.40) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL27041175 | 0.68 | HPRT1 (0.40) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL27041171 | 0.68 | HPRT1 (0.40) | MEN1TSHRKMT2ATYMPTK1 | |
| SCHEMBL31273993 | 0.67 | KDM4E (0.32) | TYMPTK1PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133876-A2 | OLIGONUCLEOTIDES COMPRISING ACYCLIC AND ABASIC NUCLEOSIDES AND ANALOGS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |