Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575493 | 0.83 | MEN1 (0.48) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL2570529 | 0.82 | MEN1 (0.40) | MEN1KMT2ATSHRTYMPTK1 | |
| SCHEMBL14955126 | 0.80 | MEN1 (0.49) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL11206457 | 0.74 | MEN1 (0.45) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL31273993 | 0.72 | KDM4E (0.32) | TYMPTK1HPRT1PDE9A | |
| SCHEMBL2577685 | 0.72 | CTSK (0.36) | TYMPHPRT1 | |
| SCHEMBL27041198 | 0.71 | HPRT1 (0.40) | MEN1KMT2ATSHRLMNASMN1; SMN2 | |
| SCHEMBL27041171 | 0.71 | HPRT1 (0.40) | MEN1KMT2ATSHRLMNASMN1; SMN2 | |
| SCHEMBL27041175 | 0.71 | HPRT1 (0.40) | MEN1KMT2ATSHRLMNASMN1; SMN2 | |
| SCHEMBL10816275 | 0.71 | MEN1 (0.47) | MEN1KMT2ATSHRPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133876-A2 | OLIGONUCLEOTIDES COMPRISING ACYCLIC AND ABASIC NUCLEOSIDES AND ANALOGS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |