Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.57 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106447 | 0.92 | CYP2C19 (0.43) | TPMTHCAR1CNR2CYP2C9CYP2C19 | |
| SCHEMBL3403399 | 0.92 | TPMT (0.43) | TPMTHCAR1CYP2C9CYP2C19SLC7A5 | |
| SCHEMBL6577887 | 0.92 | TPMT (0.43) | TPMTHCAR1CYP2C9CYP2C19SLC7A5 | |
| SCHEMBL16406592 | 0.88 | TPMT (0.48) | TPMTHCAR1CNR2CYP2C9CYP2C19 | |
| SCHEMBL20894429 | 0.85 | KDM4E (0.47) | TPMTSLC7A5CA12CA1CA2 | |
| SCHEMBL7058435 | 0.84 | CA12 (0.47) | CYP2C9CYP2C19NPSR1SLC7A5CA12 | |
| SCHEMBL20928667 | 0.84 | SLC7A5 (0.38) | TPMTHCAR1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5093115 | 0.84 | NOTUM (0.42) | TPMTHCAR2CYP2C9CYP2C19SLC7A5 | |
| SCHEMBL21015932 | 0.81 | SLC7A5 (0.40) | TPMTCYP2C9CYP2C19SLC7A5RXRA | |
| SCHEMBL16518349 | 0.80 | NOTUM (0.42) | TPMTCNR2CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121970-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | BEAM THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |